Top Kansas City AI Companies

27Global helps enterprises deploy governed agentic AI solutions, including human-agent workflows, AI orchestration, and agent-ready data and cloud platforms.

360 Automation AI is a Kansas City consultancy that builds custom AI agents, voice AI, and workflow automation for local businesses.

ActionableOps provides fractional AI leadership, AI training, and AI implementation services that help businesses put AI to work in their operations.

AI Experts KC provides AI consulting, training, and custom AI tool development built on platforms like Claude, ChatGPT, and Copilot.

Ainstein designs millimeter-wave radar sensing hardware and AI algorithms for aerospace, automotive, and IoT applications, with deployments in more than 40 countries.

Apex Resolution is an AI implementation firm that builds follow-up, booking, intake, and CRM workflows, plus AI agents that handle first-round calls and texts, inside the tools a business already uses.

Archia provides an AI agent operating system that lets companies safely deploy and manage AI agents across multiple providers through a single API, with built-in security and compliance.

AutoAlert provides AI-driven data mining and CRM software that helps auto dealerships identify high-intent customers and sales opportunities. Acquired by Atlanta-based PureCars in 2026, it maintains an office in Kansas City.

Block and Mortar builds an AI-driven operating system for real estate development, using predictive analytics and large language models to coordinate developers, contractors, and financial partners from concept through construction.

BotPhone provides a fully managed AI receptionist for small businesses that answers calls 24/7, screens spam, qualifies leads, and books appointments.

C2FO operates a working capital marketplace that uses machine learning to price and match early-payment offers between buyers and suppliers in real time.

CarePilot makes an AI-native platform that automates clinical documentation and drafts orders and prescriptions for physicians, reducing administrative burden in electronic health record workflows.

Centriq is a longtime Kansas City technology training company that also builds AI solutions and trains teams on practical AI use.

Clintuition uses generative AI to create realistic patient simulations for medical education, giving learners immediate feedback on diagnosis, clinical management, and communication.

CultureVue, from Executive Development Associates, uses natural language processing and AI to show CEOs their company culture in real time without surveys.

Cyphr builds AI-native financial infrastructure, including purpose-built financial language models, that helps governments, lenders, and economic development groups assess small business readiness and deploy capital.

Cyphra Autonomy builds autonomous material-hauling robots that move materials like rebar and concrete debris on construction sites, running autonomously, by remote control, or in follow mode.

Daupler builds an AI-powered response management system that helps utilities automatically triage incidents, dispatch crews, and optimize emergency response.

Emvia combines AI with human agents to deliver 24/7 multilingual customer support and answering services for healthcare, tech, and other industries.

Heft IQ provides an AI-driven decision intelligence platform that turns supply chain and e-commerce data into real-time insights and recommended actions.

Hippalus Technologies is a software consulting firm building custom AI and machine learning models, data analytics, and digital modernization solutions for government, healthcare, and financial clients.

Innovation Dreams Strategic AI audits whether AI assistants like ChatGPT, Claude, Gemini, and Perplexity can find, describe, and recommend a business, then shows owners what to change.

JG Search Group is a health tech executive search firm that uses AI agents and analytics to match candidates with organizations.

Kalre is a Kansas City managed IT services provider offering cybersecurity, cloud support, and custom AI consulting and tools, including its EasyPrompter.ai product.

Khanect the Dots is a strategy-first consultancy that helps organizations decide where AI belongs, set practical guardrails, and redesign workflows for responsible AI adoption, along with fractional marketing leadership, training, and keynotes.

kovac.ai is a Kansas City AI enablement consultancy that helps enterprise and mid-market organizations put AI to work through AI strategy, executive training, readiness assessments, and implementation roadmaps.

Lefty Media Co is an AI discoverability studio that helps businesses get known and recommended by AI assistants like ChatGPT, Claude, and Perplexity.

Loom Security builds CINQUE, an AI-native security posture management platform that correlates identity, device, network, application, and data risk signals into unified risk views.

Magis makes an AI platform that turns courtroom audio and paper records into searchable, structured case data for specialty courts.

MoodSpark is an AI-powered companion app that helps detect signs of sadness, loneliness, and depression in elderly users and delivers personalized content to support their emotional wellbeing.

MyAnIML uses AI-powered computer vision to analyze cattle facial and muzzle images, helping predict diseases like pinkeye or respiratory illness before visible symptoms appear.

Myndset is a mobile AI coaching app that delivers mental-performance and pressure-training techniques used by elite athletes to everyday users.

Neer provides a geospatial AI platform for civil infrastructure management, helping engineers and municipalities map, model, and run simulations for water, wastewater, and stormwater systems.

Outbound AI builds conversational AI virtual agents for healthcare that automate phone-based administrative and billing work for physician practices and health systems. Headquartered in Seattle with a hub in Kansas City.

Portrayals XR combines virtual reality and AI to deliver guided emotional healing experiences for therapists, coaches, wellness centers, and individual users.

Rade Engineering builds AI agents, workflow automation, and websites for businesses.

Raise Health uses AI to analyze conversations in real time to detect early signs of depression, anxiety, and suicidal ideation, routing at-risk individuals to mental health resources.

Rebulk, formerly dScribe AI, builds an operations platform for rail and bulk logistics that uses vision AI to track railcars, terminals, and bulk inventory in real time.

Roz builds an AI compliance platform that automates review of complex documents to find control gaps and gather audit evidence, cutting audit cycles from months to hours.

Sailes builds an AI sales agent that automates end-to-end prospecting, from research and contact discovery to outreach and meeting scheduling.

Santiago & Company is an AI-first strategy and management consulting firm advising clients on generative AI implementation, growth strategy, and organizational transformation.

Sharkitect Digital is an AI transformation consultancy that helps small businesses understand where AI fits, builds the right AI or automation solution, and trains teams in AI literacy and policy.

SiteScan uses AI image recognition to turn CCTV sewer and pipe inspection footage into automatic defect coding and GIS-ready reports for water and wastewater utilities.

SourceEazy is building AI infrastructure that automates design, sourcing, and distribution for the custom-branded promotional products and uniform industry.

STEPS Consulting Group is a Kansas City AI consultancy that helps enterprises adopt AI, automation, and analytics through strategy and implementation services.

Storytailor uses AI to create personalized, illustrated stories for kids, and has expanded into bibliotherapy programs with children's hospitals.

Surya Consulting helps organizations adopt AI-assisted software development with the right standards, guardrails, and validation, alongside web and mobile modernization work.

Suvysoft builds AI-powered websites, chatbots, marketing automation, and an AI voice receptionist for small and mid-sized businesses.

TeraCrunch builds custom full-stack AI solutions, including LLM fine-tuning, AI agents, and machine learning, for clients ranging from small firms to the Fortune 500.

Tolair is an enterprise governance platform that uses AI oversight to find and recover revenue lost in gaps between disconnected business systems.

Trially is an AI platform that matches, engages, and enrolls patients for clinical trials, using LLM agents integrated with more than 16 EHR systems to speed up recruitment.

TrueAccord is a digital-first debt collection company that uses machine learning to personalize repayment outreach, with a major operations hub in Lenexa, Kansas.

VirtusX makes AI-powered computer accessories, including Jethro, a voice-activated AI mouse that transcribes, translates, and summarizes meetings, and the Phronesis AI keyboard.